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Development of a Manufacturing Method for Surgical Meshes Modified by Chitosan

Research and development

Authors:

• Niekraszewicz Antoni
  Poland, Łódź, Institute of Biopolymers and Chemical Fibres
• Kucharska Magdalena (j/w)
• Wawro Dariusz (j/w)
• Struszczyk Marcin H.
  Poland, Łódź, TRICOMED S.A.
• Kopias Kazimierz
  Poland, Łódź, Technical University of Lodz, Faculty of Material Technologies and Textile Design, Department of Knitting Technology and Structure of Knitted Products
• Rogaczewska Agnieszka
  Poland, Łódź, TRICOMED S.A.

Full text

Abstract: Two new methods for manufacturing surgical meshes modified by chitosan have been developed in the Institute of Biopolymers and Chemical Fibres (IBWCh) in collaboration with TRICOMED S.A. The first method consists in applying chitosan yarns and a non-resorbable polypropylene monofilament as raw materials for a knitted fabric with varying chitosan content. While elaborating the second method, a half-product in the form of an OPTOMESHTM Macropore surgical mesh was used. Serving as a base, the mesh was covered by a chitosan finish which formed a coating. The meshes thus modified were sterilised by ethylene oxide, and next tested in order to determine the physico-mechanical parameters, as well as to estimate the chemical and biological purity. Meshes covered by chitosan on only one side were selected for further research, as this kind of mesh promised better commercial application possibilities.

Tags: surgical meshes, modification, chitosan.

Published on issue no 3 (62) / 2007, pages 105–109.

"Fibres & Textiles in Eastern Europe" is inserted on the "ISI Master Journal List" of the Institute for Scientific Information, Philadelphia, USA (for the year 2010 has an Impact Factor of 0.629) and is indexed in Research Alert, SCI Expanded (Sci Search and Web of Science), the Materials Science Citation Index, Current Contents/Engineering, Computing & Technology; as well as by the Textile Institute, Manchester, in the Information Service; and in Toga FIZ Technik; Rapra Technology Ltd.; Elsevier Geo Abstracts; Textiles Eastern Europe - World Textile Publications; Applied Mechanics Review; Chemical Abstracts Service; Referativny hurnal; and by the European Textile Network.

The content of "Fibres & Textiles in Eastern Europe" is available by free open access on the website http://www.fibtex.lodz.pl, starting from issue No 3/2002.